Description

Liporase is an injectable enzyme that is used to dissolve hyaluronic acid (HA) fillers. HA fillers, such as Restylane and Juvederm, are commonly used to add volume to the lips, cheeks, and other areas of the face. However, sometimes patients may be dissatisfied with the results or experience complications from the filler.

Liporase is used to dissolve the HA filler by breaking down the hyaluronic acid molecules. The enzyme is injected directly into the area with the filler, and the process can take several minutes to several hours, depending on the amount of filler that needs to be dissolved.

Liporase is also used to treat complications from HA fillers, such as overfilling, uneven results, or lumps and bumps in the treated area. It can also be used in emergency situations, such as when a blood vessel becomes blocked by the filler.

It is important to note that Liporase should only be administered by a qualified and experienced medical professional. The treatment should not be used on other types of fillers, such as those made from collagen or PMMA. Additionally, while Liporase can help dissolve HA fillers, it may not completely remove all of the filler material, and additional treatments may be necessary. It is important to discuss any concerns or questions with your healthcare provider before undergoing the treatment.

Benefits of Liporase

Liporase, also known as hyaluronidase, has several benefits, particularly in the medical and aesthetic fields. Its primary function is to break down hyaluronic acid, making it an essential tool in specific scenarios:

1. Correcting Dermal Filler Mistakes:

  • Benefit: If a patient is not satisfied with the results of a hyaluronic acid-based dermal filler or if complications arise, such as overfilling, asymmetry, or the appearance of lumps, Liporase can be injected to dissolve the filler. This offers a safety net for both practitioners and patients.

2. Facilitating Drug Dispersion:

  • Benefit: Liporase is used in general medicine to help improve the absorption and dispersion of other injected drugs. When it’s administered alongside certain drugs, it can help the medicine spread more evenly.

3. Reducing Swelling:

  • Benefit: In some medical scenarios, Liporase can be used to treat edema (swelling) by breaking down hyaluronic acid, which binds water in tissues.

4. Enhancing Fluid Absorption:

  • Benefit: It can be used to increase tissue permeability, facilitating the absorption of injected fluids in cases of subcutaneous hydration.

5. Treating Vitreous Hemorrhage:

  • Benefit: In ophthalmology, hyaluronidase can be used as an adjunct in certain eye surgeries, specifically to manage vitreous hemorrhage. By breaking down hyaluronic acid, it can help clear the gel-like substance (vitreous humor) in the eye, providing better access to the surgeon.

6. Quick Action:

  • Benefit: The effects of Liporase can often be observed within hours of administration, making it a rapid solution in cases of dermal filler complications.

7. Temporary Side Effects:

  • Benefit: While there are side effects associated with Liporase, such as swelling, redness, or pain at the injection site, most of these effects are temporary and resolve on their own.

8. An Option for Sensitive Areas:

  • Benefit: For areas like the lips, where precision is crucial, and mistakes can be quite noticeable, having the option to use Liporase as a corrective measure is beneficial.

Areas of Use

Liporase is used to dissolve hyaluronic acid (HA) fillers in various areas of the face, including:

  1. Lips – Liporase can be used to reduce the size of overfilled lips or to correct uneven results from lip filler.
  2. Cheeks – Liporase can help dissolve overfilled or poorly placed cheek filler, restoring a more natural appearance.
  3. Tear troughs – Liporase can be used to correct the appearance of under-eye bags or unevenness caused by tear trough filler.
  4. Chin – Liporase can help dissolve overfilled or poorly placed chin filler, improving the balance and symmetry of the face.
  5. Nasolabial folds – Liporase can be used to reduce the appearance of overfilled nasolabial folds, improving the natural contour of the face.

It is important to note that Liporase should only be administered by a qualified and experienced medical professional. The treatment should not be used on other types of fillers, such as those made from collagen or PMMA. Additionally, while Liporase can help dissolve HA fillers, it may not completely remove all of the filler material, and additional treatments may be necessary. It is important to discuss any concerns or questions with your healthcare provider before undergoing the treatment.

Hyaluronidase FAQs

1. What is hyaluronidase?

  • Answer: Hyaluronidase is an enzyme that breaks down hyaluronic acid, a component of the extracellular matrix in the body. It is used medically to increase tissue permeability and improve the absorption and dispersion of injected drugs.

2. Why is hyaluronidase used in aesthetics?

  • Answer: In aesthetics, hyaluronidase is often used to dissolve hyaluronic acid-based dermal fillers. If a patient is dissatisfied with the result of a filler injection or experiences complications, hyaluronidase can be injected to break down the filler and reverse the effects.

3. Is the use of hyaluronidase safe?

  • Answer: Generally, hyaluronidase is considered safe when used by trained professionals. However, as with any medical treatment, there can be side effects or adverse reactions, so it’s essential to consult with a qualified practitioner.

4. What are the potential side effects of hyaluronidase?

  • Answer: Some potential side effects include swelling, redness, pain at the injection site, allergic reactions, or bruising. However, most of these effects are temporary.

5. How quickly does hyaluronidase work?

  • Answer: The effects of hyaluronidase can often be seen within a few hours of injection, but it might take up to 24-48 hours for the full effect.

6. Can hyaluronidase remove all types of fillers?

  • Answer: No, hyaluronidase specifically targets hyaluronic acid-based fillers. It does not work on fillers composed of other materials such as calcium hydroxylapatite or poly-L-lactic acid.

7. Is the effect of hyaluronidase permanent?

  • Answer: Yes, once hyaluronidase breaks down hyaluronic acid, the effect is permanent. However, the body naturally produces hyaluronic acid, so over time, the levels in the skin will gradually replenish.

8. Are there any contraindications for the use of hyaluronidase?

  • Answer: Individuals with a known allergy to hyaluronidase or any of its components should avoid the treatment. Additionally, it should not be used in areas with active skin infections or where there is a known malignancy.

9. Can hyaluronidase be used for other medical applications?

  • Answer: Yes, besides aesthetics, hyaluronidase is used in other medical scenarios, such as to enhance the dispersion and absorption of other drugs or to reduce the complications of subcutaneous fluid accumulation.

10. How is hyaluronidase administered?

  • Answer: Hyaluronidase is typically administered via injection directly into the area where the hyaluronic acid-based filler is present or where drug dispersion is needed.

Always consult with a qualified healthcare provider before undergoing any medical treatments or procedures.