Home/Dermal Fillers, GALDERMA, Restylane/Restylane® Defyne (1x1ml)

Restylane® Defyne (1x1ml)


The pack consists of:

1 x 1ml syringe
2 x 27G 1/2″ needles
20 mg/ml Cross-linked hyaluronic acid
3 mg/ml Lidocaine

Volume Discount
20+ packs: Save 1% $148.49
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Restylane Defyne is a dermal filler that is designed to address moderate to severe facial wrinkles and folds, such as nasolabial folds and marionette lines. It is made from hyaluronic acid, a naturally occurring substance in the body that helps to hydrate and plump the skin.

Restylane Defyne is unique in that it is formulated with XpresHAn Technology™, which allows the filler to move with the natural expressions of the face while maintaining its shape and structure. This means that patients can achieve a more natural-looking result that doesn’t appear stiff or frozen.

Restylane Defyne is injected into the treatment area using a fine needle. The procedure is typically quick and relatively painless, and patients can return to their normal activities immediately after treatment. Results can last up to 12 months or longer, depending on the individual and the treatment area.

Like all injectable treatments, Restylane Defyne should only be administered by a qualified and experienced healthcare professional. Possible side effects may include bruising, swelling, redness, and tenderness at the injection site, but these are typically mild and resolve on their own within a few days.

Areas of Use

Restylane Defyne is FDA-approved for the correction of moderate to severe facial wrinkles and folds, including nasolabial folds (the lines that run from the nose to the corners of the mouth) and marionette lines (the lines that run from the corners of the mouth to the chin).

However, it can also be used off-label for other areas, such as enhancing the chin, correcting the contours of the jawline, or plumping up the lips. Your healthcare provider will be able to assess your individual needs and recommend the best treatment plan for you.

It’s important to note that Restylane Defyne, like all dermal fillers, is not recommended for use in individuals with a history of severe allergic reactions or hypersensitivity to hyaluronic acid, or in those with bleeding disorders or active infections in the treatment area. It’s always best to consult with a qualified healthcare provider to determine if Restylane Defyne is the right treatment for you.


Restylane Defyne is made from hyaluronic acid, which is a naturally occurring substance in the body that helps to hydrate and plump the skin. The hyaluronic acid in Restylane Defyne is produced through a process called NASHA (Non-Animal Stabilized Hyaluronic Acid) technology, which involves cross-linking the hyaluronic acid molecules to create a gel-like substance that can be injected into the skin.

In addition to hyaluronic acid, Restylane Defyne also contains lidocaine, which is a local anesthetic that helps to minimize discomfort during the injection process.

Restylane Defyne is free from animal products and does not require any allergy testing prior to treatment. It is biodegradable and eventually breaks down naturally within the body. Overall, the ingredients in Restylane Defyne are well-tolerated by most patients, making it a safe and effective option for facial rejuvenation.